Levothyroxine tablet is cited as one of the drug products that could be safely split to cut the cost (14). However, it is a drug recognized to have a narrow toxic to therapeutic ratio with significant clinical consequences of excessive or inadequate treatment.

Yes, an underactive thyroid gland can make you feel tired all day, but some of the medications used to treat hypothyroidism may result in insomnia or the inability to fall and stay asleep. Talk to your doctor about your medication including when you take it to see if it’s playing a role in your sleeplessness.

“You should also avoid any drugs or supplements that contain iron, calcium, or magnesium for at least four hours after taking your thyroid medications,” says Dr. Jaiswal. That also includes multivitamins that contain these minerals.

These could be symptoms of too much medicine in your body. Do not suddenly stop taking this medicine without first checking with your doctor. Your doctor may want you or your child to gradually reduce the amount you are using before stopping completely.

Some endocrinologists recommend that people whose hypothyroidism symptoms persist despite normal TSH levels try adding T3 to their levothyroxine therapy. T3 is the body’s active form of the thyroid hormone thyroxine.

Levothyroxine and ferrous sulfate should not be taken orally at the same time. Products that contain iron may interfere with the absorption of levothyroxine and reduce its effectiveness. You should separate the dosing of these medications by at least 2 to 4 hours if possible.

Getting better takes time. When you start levothyroxine you won’t feel better the next day. You may not feel better in two weeks. But symptoms should start disappearing within a month. After six weeks of treatment, you should be almost completely free of symptoms, assuming you’re at the right medication level.

Summary: Contrary to popular belief, effective treatment with levothyroxine (LT4) to restore normal thyroid hormone levels is not associated with clinically significant weight loss in most people. Decreased thyroid function, or hypothyroidism, is commonly associated with weight gain.

According to a presentation at the annual meeting of the American Association of Clinical Endocrinologists in 2017, Synthroid was associated with significantly better thyroid-stimulating hormone (TSH) lab results than generic levothyroxine.

In addition to this, some have reported that they experienced mild nausea and anxiety if they took the thyroid medication and the CBD oil too closely together. However, if a few hours were allotted between the medications, there seemed to be no negative side effects for most people.